What Is Hereditary Angioedema (HAE)?
Hereditary angioedema (HAE) is a rare genetic disorder that causes sudden, severe swelling in areas such as the face, hands, abdomen, and throat. It’s typically caused by a deficiency or dysfunction in the C1 inhibitor protein, which plays a role in controlling inflammation. Unlike common allergic reactions, HAE doesn’t respond to typical allergy treatments.
Symptoms may include pain, swelling, and discomfort that can interfere with daily activities. Episodes may occur without a clear trigger, and both children and adults can be affected. HAE is inherited, meaning it can run in families, though symptoms and severity vary between individuals.
How You Can Help Advance HAE Research
At Equity Medical, we run clinical trials for hereditary angioedema at our research sites in New York and Kentucky. These studies help researchers explore how HAE symptoms progress, how different people respond to investigational therapies, and what future care options may emerge.
All trials are overseen by board-certified allergists, pediatricians, and internists focused on safety, transparency, and supporting every participant through the process.

You May Be Eligible If You:
Submitting your interest does not enroll you in a study. If there’s a current trial that may be a good fit, a member of our team will reach out to share more details.
Why Join a Clinical Trial
Why Participants Choose Equity Medical
Equity Medical is committed to accessible, supportive, and respectful clinical research. If you join a hereditary angioedema study with us, you’ll work with a knowledgeable team that values your time and experience. Our centers in Bowling Green, KY, and New York City (Upper West Side of Manhattan and the South Bronx) offer flexible scheduling and a welcoming research environment.


